Abstract: This present investigation deals with evaluation of anti-inflammatory potential of ethanolic extract of Trigonella Foenum graecum L. (Fenugreek) seeds and demonstration of its effectiveness by formulation of a gel containing the extract. The extract was first analyzed for potential anti-inflammatory phytochemicals and then gel formulations weredesigned by using ethanolic extract of fenugreek seeds extract in moderate concentration (5%) and evaluated using physiochemical and physiological measurements.