Abstract: Different plant extracts of Carica papaya (papaya) peels were investigated for their antioxidant capacity (AOC), antibacterial activity, antidiabetic activity and concentration of carotenoids content. An investigation was carried out to identify the best extraction conditions to obtain a suitable extract that can be used to formulate a fish feed with important bioactivities. Three different papaya peel drying methods and a suitable solvent to use with the maceration technique was tested. According to the UV-Visible spectra of the extracts, the highest percentage of carotenoids was obtained for the ethyl acetate extract of air-dried sample (5.4 µg/mL).