Abstract: A survey was carried out in District Hamirpur for documentation and information from natives about the ethno-medicines uses of plants. The indigenous knowledge of local uses of plants by natives,was collected through personal interviews during field of this hilly district of Himachal Pradesh.The communities in the different villages of this district are gathering the long-hidden indigenous knowledge . From my whole study I found that plants of Fabaceae and Solanaceae families are widely used, by the natives ; 12 plants from Fabaceae and 8 plants from Solanaceae family I reported.