Abstract: The methylene blue (MB) absorption onto neem leaf powder was investigated in term of both adsorption efficiency and kinetic study. The effects of operation parameters i.e., MB concentration, time of adsorption, adsorbent dosage, pH of solution and temperature were investigated. The results showed that all parameter could affect the adsorption efficiency. The adsorption isotherm and kinetics over various pH and temperature were also studied. It was found that the adsorption capacity was increased with pH and temperature increased; suggested the exothermic process. The experimental data showed that the MB adsorption was fitted with Langmuir isotherm and the kinetic model was the pseudo-second order.