Abstract: Rhabdomyolysis is the consequence of some diseases commonly seen in the emergency services, with several complications. In addition, there are lots of Rhabdomyolysis protocols in different countries and also in Brazil, with many points of agreement and others with divergent opinions, like the time of drugs administration and their posology. There are many variations and little evidences in the few studies and researches on humans.. Objectives: This paper aims to discuss the various protocols and reviews existing literature in order to adapt them to our institutional reality and the best treatment protocol. Methods: This study analysed protocols and updated concepts on Rhabdomyolysis. An non systematic review of protocols of all over the countries was performed. Results: All protocols focus on hydration and in a earlier diagnosis. Support treatments differs from service to service. Discussion and Final Comments: We hope that this study and research standardise the current treatment of the Rhabdomyolysis, based on evidences and clinical findings of various countries and thereby decrease the risk of it’s most important complication: acute renal failure.