Abstract: Kidney is a vital organ of the body that plays a crucial role in filtering blood, removes including elimination of drugs maintaining fluid and electrolyte balance, releasing hormones to control blood pressure, stimulate red blood cell production, activating vitamin D to produce calcium leading to maintain bone health. Acute renal failure and chronic kidney disease are the two main conditions in renal failure. This study shows that managing of co morbid conditions hypertension, diabetes, coronary heart disease, congestive heart failure, left ventricular hypertrophy, infections, renal calculi, pulmonary diseases which are very essential in treatment of renal failure.