Abstract: Meningioma is the most frequently diagnosed primary tumor of the central nervous system, with higher prevalence in females and increasing incidence in older individuals. This study aimed to evaluate the clinicopathological characteristics of patients diagnosed with meningioma at Sembiring General Hospital from 2021 to 2024. A retrospective descriptive method was employed using secondary data from medical records of patients who underwent craniotomy and histopathological examination. Seventeen cases were identified during the study period. The highest number of cases was reported in 2023. Female patients constituted the majority (64.7%), with the age group of 41–50 years being the most affected. Interestingly, meningioma cases in the 61–70 age group were more commonly found in male patients. Histopathological analysis showed that the most prevalent subtype was meningothelial meningioma, and the majority of tumors were classified as WHO Grade I. Higher-grade variants, such as atypical and anaplastic meningiomas, were rare. These findings are in line with global trends, indicating a predominance of benign meningiomas in middle-aged women and a rising incidence among older men. The study provides local data that may support clinical decision-making and serve as a reference for future research on meningioma in similar settings.