Abstract: Background: Health And safety is a series of safeguards and guarantees of safety and health by improving the health status of workers by preventing accidents and occupational diseases with activities of preventive, promotive, curative, rehabilitation. Based on data from the International Labor Organization (ILO) states that 2.78 million workers worldwide die each year due to accidents at work and occupational diseases. About 86.3% of the causes of death for workers are occupational diseases. According to the World Health Organization (WHO), burnout is included in the 11th revision of the International Classification of Diseases (ICD-11) as an occupational phenomenon. Several studies explain that there is a relationship between self-efficacy, social support, work stress on the incidence of burnout in nurses in hospitals.