Abstract: The general objective of this study was to assess the role of leadership and strategic implementation in humanitarian agencies in Rwanda. Cross-sectional and descriptive research designs were used. The total population was 247 from which 153 respondents were selected as sample using stratified random sampling technique. Data collection methods involved questionnaire, documentation analysis and interview. Analysis of data was done through SPSS, version 20. As indicated, research findings. The findings revealed that the four models tested using ANOVA for competence of staff, communication of strategic implementation, the amount of resources deployed and the number of people attending training were statistically significant with leadership as measured by inspiring trust, vision creation, in executing strategies and in coaching potentials. The research recommended the use of leadership style which allows for interaction and transformation for strategic implementation.