Abstract: Central venous access is common procedure for long term medication in oncology patients. Various options are available with each having its benefits and risks associated. A study with aim to see the change in trend in central venous access in adult cancer patients at our institute comparable with international standards was performed over a period of one year for patients who had central venous access. All central venous access procedures done in adult cancer patients were included. Number of patients, primary cancer histology and site and complications after each procedure were observed and analyzed. Total number of patients, gender, frequency and type of malignancy and method of central venous access along with its complications were observed. A rise in referrals for port A catheter in the last 6 months with decreasing referrals for PIC and broviac catheters was noted former having least complications.