Abstract: Background: Cervical squamous cell carcinoma NOS cervix It is an invasive epithelial tumor with varying degrees of differentiation. The prognostic grading system based on WHO (2020) is assessed from nuclear pleomorphism, mitosis, tumor cell invasion, keratin, and necrosis. Tumor budding is an isolated tumor cell bud 5 cells.1 This tumor budding phenomenon is considered the histological basis for the formation of metastases and further tumor invasion which is an independent prognostic, especially in cervical squamous cell carcinoma NOS.15