Abstract: A field experiment to detect the response of different rice genotypes against rice blast disease under DSR condition at Mid hill during rainy season of 2017. Screening of different genotypes was carried out in a field against rice blast disease and checked in one factor RCBD with 3 replication and 9 genotype. The experiment was conducted to impart knowledge about the response of different genotype against rice blast disease. The disease severity, AUDPC was found high in Shankharika genotype while found low in Sabitri genotype. Thus the use of Sabitri genotype provide proper resistance against rice blast disease in rice under the hill region of Baitadi district under Direct Seeded Rice(DSR) condition.