Abstract: Despite that antimicrobial resistant (AMR) is not a new problem around the world. The number of resistance microorganisms reaches an alarming level increasing morbidity and mortality across different geographical places. World Health Organization (WHO) defined the actual situation of AMR as natural phenomena when the microorganisms adapt and develop their ability to survive and multiply in the presence of antibiotic which was previously susceptible to kill or inhabit this type of organism [1]. Causing diseases agents that were thought to be under control by antibiotics to return in new types of resistance to their therapies.