International Journal of Scientific and Research Publications

IJSRP, Volume 8, Issue 6, June 2018 Edition [ISSN 2250-3153]


NEW ADVANCED SYNTHETIC APPROACH ON PHARMACOPHORE 1,2-AMINO ALCOHOLS
      B.Sreekanth, Dr C.M.Bhaskar Reddy, Dr S.G. Manjunatha
Abstract: The main aim and objective of this research paper is to prepare pharmacophore 1, 2- amino alcohols. Amino alcohols are prepared by ring opening with nitrogen nuclophiles from Cyclicsulfates which was consequentialised via asymmetric dihydroxylation of the corresponding alkenes. 1,2-amino alcohols prepared by ring opened with nitrogen nuclophiles from carbonates which was derived via asymmetric dihydroxylation of the corresponding alkenes. The opening occurs in the generally activated position with overall yields of 70-80% . Similarly, synthesised syn-amino alcohols from syn-diols. These compounds are more useful to cure infections obtained from Gram positive and Gram negative Bacteria in human beings.

Reference this Research Paper (copy & paste below code):

B.Sreekanth, Dr C.M.Bhaskar Reddy, Dr S.G. Manjunatha (2018); NEW ADVANCED SYNTHETIC APPROACH ON PHARMACOPHORE 1,2-AMINO ALCOHOLS; Int J Sci Res Publ 8(6) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0618.php?rp=P787476
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