International Journal of Scientific and Research Publications

IJSRP, Volume 5, Issue 6, June 2015 Edition [ISSN 2250-3153]


Clinical Profile and Outcome of Malaria Patients with Acute Kidney Injury
      Dr. K.S. Amaravathi, Dr. P. Shakuntala, Dr. B. Sudarsi, Dr. N. Srinivasa Rao, Dr. R. Nagamani, Dr. P. Ramya
Abstract: Malaria has protean clinical manifestations and renal complications, particularly acute kidney injury that could be life threatening. This study was a prospective study of 50 patients with malaria-associated AKI at our hospital. Smear positive and Parasite V and F positive malaria patients with AKI as defined by RIFLE (Risk, Injury, Failure, Loss of kidney function, and End-stage kidney disease) classification were selected to evaluate the clinical profile and outcome. Out of 50 patients in our study 38 were males and 12 were females. 42% were between 26-40 years. Fever was the most common presenting complaint (100%), followed by chills and rigors (90%), headache (74%), vomiting (70), myalgia (60%), altered sensorium (30%) and discolouration of sclera (36%). Pallor (62%) was the most common sign followed by splenomegaly (62%), icterus (40%) and hepatomegaly (34%). Artemesinin combination therapy was given for all patients and renal replacement therapy was given to 12 (24%) patients. We had a mortality of 12%, all of them had multiple complications. Acute kidney injury in malaria occurred most commonly in plasmodium falciparum 70% infected patients. Applying RIFLE criteria helps in early identification of high risk cases, so that prompt treatment is instituted early, thereby reducing the mortality rate.

Reference this Research Paper (copy & paste below code):

Dr. K.S. Amaravathi, Dr. P. Shakuntala, Dr. B. Sudarsi, Dr. N. Srinivasa Rao, Dr. R. Nagamani, Dr. P. Ramya (2018); Clinical Profile and Outcome of Malaria Patients with Acute Kidney Injury; Int J Sci Res Publ 5(6) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0615.php?rp=P424246
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