International Journal of Scientific and Research Publications

IJSRP, Volume 5, Issue 6, June 2015 Edition [ISSN 2250-3153]


Role of Serum Cholesterol Level in Pathogenesis of OCD
      Dr Madhura TK
Abstract: Etiology and pathophysiology of obsessive compulsive disorder remains inconclusive till today. Multiple converging lines of evidence suggest that neurobiology plays a significant role in the etiology of obsessive compulsive disorder (OCD). Certain brain areas frequently involved in symptomatology of OCD, analyzed by neuroimaging studies. The strongest pharmacologic evidence concerns the serotonergic system and the well-established efficacy of potent serotonin reuptake inhibitors in the treatment of OCD. Cholesterol forming the vital component of neurons regulates neurochemical activity. Reduced serum cholesterol level causes hyperactivity of serotonin reuptake receptor activity precipitating symptoms of OCD.

Reference this Research Paper (copy & paste below code):

Dr Madhura TK (2018); Role of Serum Cholesterol Level in Pathogenesis of OCD; Int J Sci Res Publ 5(6) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0615.php?rp=P424148
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