Abstract: Prevalence of Urinary stones is increasing in the society due to high protein rich, salty diet with less physical exercise. In Ayurveda it is described as a Mutrashmari and manages through the detoxifying and pacifying the vitiated doshas. A 33 year old patient with 3 to 4 stones in all calyces of either kidney treated with single drug therapy of Unex capsule of Unijules Life Science Ltd. for three month and he got total cure without any pain etc.