IJSRP, Volume 3, Issue 6, June 2013 Edition [ISSN 2250-3153]
Emmanuel Uttah, Emmanuel Ogban, Christiana Okonofua
Toxoplasmosis is an epidemiological paradox. It is one of the most prevalent and most widespread parasitic infections, yet one of the most ignored of all human infections. Between 30% and 65% of all persons worldwide are infected with Toxoplasma gondii, the causative organism. It is a coccidian parasite that infects mostly species of warm-blooded animals including man. It is asymptomatic among immunocompetent persons but presents a spectrum of clinical manifestations among the immunocompromised. Approximately 10% of congenital toxoplasmosis results in abortion or neonatal death. Infection may be associated with other diseases such as HIV/AIDS in humans or immunosuppressive therapy in any species. Toxoplasma encephalitis reportedly develops in approximately 40% of individuals with AIDS, and is fatal in 10-30% of these cases. This paper discussed updates and research trends on the biology, epidemiology, transmission, diagnosis, treatment of toxoplasmosis and made recommendations.