Abstract: The triglyceride glucose (TyG) index is a simple and inexpensive technique for assessing the risk of ischemic heart disease (IHD). This review summarizes the existing evidence on the TyG index and its higher predictive value as a predictor of ischemic heart disease when compared to other markers. Recent research has found a link between higher TyG index values and an increased risk of IHD, independent of established cardiovascular risk factors. Although optimal cutoff values have yet to be determined, the TyG index is a promising tool for predicting IHD risk due to its ease of use and potential clinical applicability. More research is needed to prove its clinical utility and potential for use in clinical decision-making.