Abstract: The study was carried out to evaluate the activities of soil microorganism influenced by oil palm cultivation in a coastal plain sands area of Akwa Ibom State Nigeria. Four locations were identified, namely: oil palm plantations or block of 57 years (B-57), 39 years (B-39), 17 years (B-17) and a no oil palm block (B-0). Three representative profile pits were sunk in each location and soil samples were collected for laboratory analyses in the wet and dry seasons. The result showed that oil palm slightly increased the bacterial density as well as the respiration rate of the soil of the study area. The trend was as follows: B-39> B-17> B-0> B-57. Bacterial density was significantly (P>0.05) higher in the wet season than in the dry season in three of the locations. Microbial activities increased with the age of oil palm up to 39 years, then decreases as the palm ages.