Abstract: The aim of this study to evaluate whether or not Body Mass Index (BMI) is associated with the severity of Acute Calculus Cholecystitis. In this study 50 patients were enrolled and categorized as obese (BMI ≥25 kg/m2) and non-obese (BMI< 25 kg/m2). There was a significant association between BMI and severity of ACC (p=0.01). Similarly, the severity of ACC was more in obese female patients (p=0.05) whereas such association was not observed in obese male patients (p=0.18). Increased BMI is associated with severe form of ACC.