International Journal of Scientific and Research Publications

IJSRP, Volume 3, Issue 5, May 2013 Edition [ISSN 2250-3153]


Aleukemic Variant of Mast Cell Leukemia- A Rare Phenomenon
      Brij Mohan Kumar Singh, Chethan Manohar, Deepak Nayak M, Sushma V. Belurkar
Abstract: Mast cell leukemia is a rare variant of mastocytosis, accounting for less than 1% of all mast cell disease and pose one of the greater challenges in the management of these patients, with a grave prognosis. Diagnosis of this neoplasm rests on the detection of abnormal mast cells in marrow and subsequent spill over to the peripheral blood. We report a case of aleukemic variant of mast cell leukemia in a pediatric patient, presenting with fever and chest pain for 10 days. The peripheral smear showed a picture of pancytopenia with abnormal/ atypical lymphoid cells. Bone marrow aspirate showed dense aggregates of atypical, hypogranular and partially degranulated mast cells expressing toluidine blue and CD117 positivity.

Reference this Research Paper (copy & paste below code):

Brij Mohan Kumar Singh, Chethan Manohar, Deepak Nayak M, Sushma V. Belurkar (2018); Aleukemic Variant of Mast Cell Leukemia- A Rare Phenomenon; Int J Sci Res Publ 3(5) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0513.php?rp=P171185
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