Abstract: This study sought to determine nutrition knowledge and its association with practices in management of stage 5 chronic kidney disease (CKD) among renal adult patients in Kenyatta National Hospital. A cross-sectional analytical design was used to facilitate collection of qualitative and quantitative data and enable identification of associations between variables. Cochran formula was used to calculate a sample of 110 respondents. A research administered questionnaire with closed ended questions was used to collect information.