Abstract: Quality management approach is an important tool which holds the key to competitiveness in the global market irrespective of the size of the company. It is an integrated management approach that aim to improve continuously the performance of products, processes, and services to achieve and surpass customer’s expectations. To accomplish this objective, some key factors i.e. critical success factors (CSFs) that contribute to the success of Quality Management efforts are identified for the growth of Large and Medium Scale Organization. Through a Comprehensive review of literature it is observed that the survey at various manufacturing and service industries is carried out and it is found that the integration of CSF’s and Total Quality Management is useful for the quality improvement. The purpose of this study is to identify CSFs for the benefit of Large and Medium Scale Industries. The various CSFs identified for industries are Top management support, Training and Education, leadership, Employee Involvement, Organizational Culture, continuous Improvement, working Environment, Technical adequacy, customer focus and Quality assurance.