Abstract: This study aims to discover and understand the application of the doctrine of pre-emtive military strike against the existence of the principle of self-defense and the principle of non-intervention in an attempt to establish a new international legal provisions. The method used in this study is a normative legal research methods. The results showed that application of the doctrine of pre-emtive military strike is, the development of the interpretation of Article 51 of the UN Charter and raises the pros and cons among academics and practice of the countries in the world, so it can affect the formation of a new international law. Conclusion : The doctrine of pre-emtive have strayed or not in line with the principle of self-defense in international law.