Abstract: Air pollution has been identified as one of the silent killers in the present world as pollutants are taking lives of people without making any noise. Unlike other disasters, air pollution destroys human life gradually. People can see and people can predict when disasters occur. However, people cannot understand or cannot see when air pollution is taking place until people are seriously affected. The road transport and traffic significantly contribute to degrade the quality of air in any region of the world. This study attempts to examine the spatial pattern of Sulfur dioxide and Nitrogen dioxide in the city of Colombo using the data collected by the National Building Research Organization (NBRO), Sri Lanka from January, 2003 to December, 2005. Some socio-economic data which are used as explanatory variables for the spatial pattern of air pollutants were collected from different government organizations.