Abstract: The endometrium plays an important role in the success of a pregnancy. There have been many clinical treatments that have been tried to increase endometrial thickness. These include hormone replacement, growth hormone and aspirin. However, they face numerous difficulties. The platelet-rich plasma method (PRP), was therefore considered. Infertile women suffering from recurrent implantation loss (RIF) or thin endometrium have been treated with intrauterine autologous plasma (PRP). Twelve patients with infertility between the ages of 25 and 40 were chosen for PRP treatment. The data suggests that PRP treatment may improve endometrial thickness as well as receptivity. The study concluded that PRP is effective in increasing endometrium thickness, which can lead to clinical pregnancy.