Abstract: Systematic lupus erythematosus (SLE) is a long-term autoimmune disease (a chronic condition) that results from malfunctioning of the immune system with severity from mild to life-threatening (1). It can cause rash, arthritis, serositis, nephritis, seizures, or psychosis, which might be continuous in some cases (2). There is a high incidence of SLE in black Caribbean females (33/100000), whereas in India it is 9.9/100000 (1). The disease has a female preponderance, especially among women of childbearing age (3). In spite of the fact that SLE is the most common autoimmune rheumatic disease encountered in pregnancy, modern drug therapies and management have helped many women who are of childbearing age to conceive. SLE-suffering women have a higher fetal and material risk during pregnancy than healthy women (4). When SLE has been quiescent for six months or more before getting pregnant, the prognosis for both mother and child is best.