Abstract: The phenomenon of performance of government programs is extensively researched across the globe. However, the influence of monitoring and evaluation planning on the performance of government programs remains a grey area. The study sought to examine the influence of monitoring and evaluation planning on the performance of government programs using a case study of Uganda Women Entrepreneurship Program in Busoga, Uganda. Using a cross-sectional survey design, quantitative and qualitative date were collected from a random sample of UWEP beneficiary groups and a non-random sample of UWEP supervisors from Jinja, Iganga and Kamuli districts. The data was analyzed quantitatively and qualitatively. The findings indicated a Pearson's correlation coefficient of 0.755 with a corresponding probability that was less than 5%. The study concluded that monitoring and evaluation planning was a significant factor in the performance of government programs more so, the Uganda Women Entrepreneurship Program in Busoga.