Abstract: The therapeutic effects of plants are attributed to their phytochemicals. Consequently, the preliminary screening of phytochemicals has become an invaluable step in the discovery of pharmaceutical drugs. There is currently no information available in the literature on the phytochemical composition of Samoan medicinal plants. This study presents for the first time the quantification of some phytochemicals present in eight commonly used Samoan medicinal plants – Syzygium inophylloides, Clerodendrum inerme, Kalanchoe pinnata, Vernonia amygdalina, Homalanthus nutans, Annona muricata, Chamaesyce hirta, and Morinda citrifolia.