International Journal of Scientific and Research Publications

IJSRP, Volume 10, Issue 9, September 2020 Edition [ISSN 2250-3153]


Analgesic Properties of Crude Aqueous Extract of Senna occidentalis Leaves in Wistar Albino Rats by Tail Flick Method
      Bargu Sulaiman Jibril, Sule Ayuba Chul, Abba Aji Mustapha, Goni Babagana
Abstract: Senna occidentalis leaves were collected at Maiduguri Metropolitan Council (MMC) of Borno State, Nigeria and extracted in water by simple maceration method. The aqueous extract was tested for its analgesic activity in Wistar albino rats by tail flick method, where the result showed significant (P<0.01) increase in reaction time from 6.60±0.20 to 8.00±0.32 compared with the control (5.00±0.00) for the extract graded doses of 200 to 600 mg/kg, at 30 minutes post treatment; 7.20±0.37 to 8.60±0.24 compared with the control (4.60±0.24) for the same graded doses of the extract, 60 minutes post treatment; 5.60±0.24 to 7.60±0.24 compared with the control (4.60±0.24) for the same graded doses of the extract, 90 minutes post treatment; and 5.20±0.20 to 6.40±0.24compared with the control (4.60±0.24) for the same graded doses of the extract, 120 minutes.

Reference this Research Paper (copy & paste below code):

Bargu Sulaiman Jibril, Sule Ayuba Chul, Abba Aji Mustapha, Goni Babagana (2020); Analgesic Properties of Crude Aqueous Extract of Senna occidentalis Leaves in Wistar Albino Rats by Tail Flick Method; International Journal of Scientific and Research Publications (IJSRP) 10(09) (ISSN: 2250-3153), DOI: http://dx.doi.org/10.29322/IJSRP.10.09.2020.p10531
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