Abstract: Social media websites are the most common activity of today’s youth students. The main purpose of this study was to investigate the relationship between social media usage and Self-esteem among Wolaita Sodo University students. The research employed cross-sectional survey research design with quantitative approach of data analysis. From the total population of 11,650 (7,174 males and 4,473 females) students, 763 (470 males and 293 females) students were selected by using systematic random sampling technique after employing stratified random sampling technique to select participants based on sex, year level and College. The finding of the study revealed that the major purpose of social media usage among Wolaita Sodo University students was to have good relationships with others and in touch with friends and family.