Abstract: Today, the rate at which deviant behaviours occur in the workplace have become so worrisome as well as harmful to the wellbeing of the organization which is presently prevailing in most organizations including the hospitality industry. Thus, the purpose of this paper is to study the relationship that exist between employee work isolation and deviant behaviour in the hotel industry within the South-South Region of Nigeria. A survey design was adopted using questionnaire as the research instrument which was distributed to 291 employees of three selected hotels in the South-South region of Nigeria. The data derived were analyzed through the use of Spearman’s Rank Order Correlation Coefficient Statistical as well as t-statistics to test the relationship between the variables of the study through the use of Statistical Package for Social Sciences within a significance level of 0.05.