Abstract: This study investigated the effect of Computer-Assisted Model on Upper Basic III Students’ Attitude towards Drug Abuse Education. Purposive sampling procedure was employed to select 85 upper basic III students from two public co-education schools in West Senatorial District, Nasarawa State, Nigeria. Quasi experimental design was employed for the study. Two research questions guided the study and two research hypotheses were tested at 0.05 level of significance. Attitude Towards Drug Abuse Education Questionnaire (ATDAEQ) was used as instrument for data collection.