Abstract: This study examined Awareness and knowledge of health workers towards professional team work in hospitals in Northern senatorial district of Cross River State, Nigeria. To achieve the objective of the study, three specific objectives were developed from which three research questions were stream - line for the study. The study adopted a social survey research design and a questionnaire was used to gather information. A sample of 250 health professionals were randomly drawn from three hospitals from the area for the study. A structured questionnaire was used to obtain the opinion of the health workers and percentage was used to analyse the data.