Abstract: The main purpose of this study was to figure out the student perception for English as a Second Language by using YouTube. The questionnaire of 19 items was sent to fifty ESL participation in a University in Phnom Penh City in order to identify students’ interests of YouTube in ESL classroom and to find out the students’ perceptions of using YouTube in ESL classroom. There were 50 participants who responded to the questionnaire and 22 males and 28 females.