Abstract: Background: Patients taking atypical antipsychotics are in danger of antipsychotic-induced weight gain. Weight increases rapidly in the initial period after starting antipsychotics. Cardiovascular and cerebrovascular morbidity and mortality and reduced quality of. Both nonpharmacologic prevention and intervention strategies have shown modest effects on weight. Changes in physical appearance can lead to body image issues and problems with self-esteem, which in turn could lead to poor compliance with medication.