Abstract: The success and draw backs of the compression molding are well studied and reported but there is no enough studies or reports on injection molding. This study is on a comparison and evaluation of palatal adaptation of two different denture bases fabricated in two different palatal forms namely Shallow palate and Deep palate were used. Orientation notches (OrN) were made in the Master Model and were duplicated. 20 Shallow and 20 Deep palate cast were made. Denture bases were processed by Compression molding and Injection molding technique. The casts were trimmed in the PPS area and midline and the palatal adaptation was evaluated using vision measuring system. The results revealed that the mean palatal adaptation of injection molding denture bases was statistically significant when compared to compression molding denture bases in both the shallow palate and deep palate (p≤0.05). But there was no statistical difference within the injection molding and compression molding denture bases in both palates (p≥0.05). The Injection molding denture bases had better palatal adaptation. The material of choice and the technique of processing plays a major role than the shape of the vault in deciding the palatal adaptation of the denture.