Abstract: This study is designed to relate the Cox Proportional Hazard model to evaluate the determinant factors of survival time, predict the clinical progression of HIV/AIDs ailment by means of secondary data obtained from the Antiretroviral Rehabilitation Unit of Central Hospital, Agbor, Delta State, Nigeria. The statistics were extracted from Regular Patient Medical Registration. A study was undertaken on a sample of 1000 HIV/AIDs patients who were followed for a minimum predetermined period of 11 years and 3 months. From the sample, 64.2 per cent were female and 35.8 per cent were male, 8.6 per cent of the patients were report dead; while 91.4 per cent patients were censored. The Cox regression result indicated that the survival time of the HIV/AIDs patient is significantly related to gender, on ART, enrolment date, and current age.