Abstract: The main purpose of this study is to examine the casual model and explain the relationship of opportunism, conflict, trust, commitment, satisfaction, and loyalty between hospitals and their suppliers. A survey is conducted of local community hospitals, regional hospitals and medical centers in Taiwan. Primary data is gathered using a questionnaire; this study investigates hospitals procurement staffs that are responsible for selecting medical device suppliers. The sample consists of 481 valid responses for applying structural equation modeling (SEM) in this research. The study confirms almost all hypothesized associations between the constructs examined, indicating that the supplier’s opportunistic behavior reduces trust and generates conflict. According to the significant mediation effect, showed that commitment plays a mediated role between trust and satisfaction, and satisfaction is a mediated factor to loyalty. Thereby displaying trust in addition to being an important factor in the success of supply chain management, but also an important factor in the success of alliances.