IJSRP, Volume 4, Issue 4, April 2014 Edition [ISSN 2250-3153]
T. Rajendran, K. Senthil Murugan, G. Balakrishnan, C. Karthikeyan, S. Thanaraj, G. Arunkumar, V. K. Sivasubramanian, M. Ganesan, K. Vijaya
Six transition metal-salen complexes (metal = Fe, Mn and Cr) 1-6 have been synthesized and characterized using different spectroscopic and electrochemical techniques. The binding studies of natural antioxidant, curcumin with the complexes (1-6) have been carried out by electronic absorption spectroscopic technique. The substantial shift in the absorption maximum of complexes (1-6) when they bind to curcumin indicated that there was a strong binding between them. The binding constant calculated ranges from 20 to 2.46 X 104 M-1 s-1. To the best of our knowledge, this is the first report for studying binding nature of curcumin, the natural antioxidant with these biologicallly relevant metal-salen complexes.
T. Rajendran, K. Senthil Murugan, G. Balakrishnan, C. Karthikeyan, S. Thanaraj, G. Arunkumar, V. K. Sivasubramanian, M. Ganesan, K. Vijaya (2018); Binding of Natural Antioxidant, Curcumin with Metal-Salen Complexes;
Int J Sci Res Publ 4(4) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0414.php?rp=P282584