Abstract: Ayurveda, the science of life identifies man as an embodiment of nature. It encloses the essential concepts in various streams of Indian philosophy. Theory of instantaneous or ksanikavada is a significant concept in Buddhism, according to which all the universal things are momentary. A similar thought can be seen in Ayurveda known as Svabhavoparama or natural destruction, this expounds that all the things are in a succession of natural destruction. According to this theory, the process of ending occurs without a specific reason. Even though there are numerous conceptual similarities in the Buddhist and Ayurvedic doctrines, the present study mainly concentrates on the analysis of Ksanikavada and Svabhavoparamavada.