Abstract: Student motivation and engagement are key factors for effective and lasting learning. Neuroscience shows that reward mechanisms, mediated by dopamine, influence the desire to learn, while educational psychology provides theoretical models useful for instructional design. The Self-Determination Theory (Deci & Ryan, 1985) highlights the role of autonomy, competence, and relatedness in intrinsic motivation, while the theory of learning goals (Dweck, 2006) distinguishes between a fixed and growth mindset, with significant implications for teaching. Strategies such as gamification, cooperative learning, and motivational feedback enhance school engagement.