Abstract: COVID-19 introduced a modern normlessness, collapsing social support structures required for encouragement during rapid changes such as social distancing, job loss and psychological distress. The purpose of this research is to determine if there is a significant relationship between unemployment and suicide and to examine whether this association is affected by the COVID-19 pandemic. We conducted a regression analysis to analyze the variances in the number of unemployment and suicides from 1999–2018 in the U.S. Results of the simple linear regression indicated that there is a significant relationship exists between unemployment and suicides, (F(1, 18) = 59.58, p<.001, R2=.768), concluding that higher unemployment rates will increase the number of suicides. Preventing suicide calls for immediate action accompanied by mitigation initiatives and exposure to mental health treatments to ensure that individuals with diminished or unforeseen income have access to appropriate resources.