Abstract: The education system in Nigeria is faced with a mirage of defects which include inadequate provision of teaching and learning resources as a result of poor planning and corruption among other things. This study considers the effect of teaching/learning resources on academic performance in mathematics among pre-university students in Ile-Ife, South-West, Nigeria. A total of 126 questionnaires were administered among two major pre-university schools in Ile-Ile, Nigeria. The research instrument developed for this research is student’s questionnaire on performance (SQP) to answer at least three research questions on academic performance of students in mathematics. Correlation analysis, coefficient of determination and multiple regression analysis were used to analyze the data. In all analyses, we find that all the independent variables considered could not account well for academic performance of students in mathematics. Cogent recommendations were made based on our empirical findings.