Abstract: Intra-Africa trade is one of the most upcoming approaches of economic growth within the continent of Africa through regional economic integrations established. East Africa Community is one of the newly upcoming strong regional integration with the aim of creating harmonious trade environment among its member countries and propels economic growth among them. This study was done to compare the trading costs and benefit between Tanzanian small and medium agro-enterprises (SMAEs) trading to EAC countries and those trading locally within Tanzania. The study collected a sample of 105 SMAEs trading to EAC countries and 105 SMAEs trading locally. Costs and Benefit Analysis tool and descriptive statistics were used and three regions of Tanzania namely Arusha, Kagera and Mwanza were involved with three types of agricultural crops Beans, Maize and Rice.