International Journal of Scientific and Research Publications

IJSRP, Volume 3, Issue 2, February 2013 Edition [ISSN 2250-3153]


Protons Confirmation of Glimepiride drug using Correlation Spectroscopy a unique tool of Nuclear Magnetic Resonance spectroscopy
      Kartikeya Dwivedi , Nitin Saraswat , Meena Bisht
Abstract: The power of Nuclear Magnetic Resonance spectroscopy (NMR) in structure elucidation derives in large part from its ability to establish bonding connectivity (via J- coupling interaction) or through space proximity (via dipolar coupling interactions) of nuclei. The amount of time consumed in elucidating a structure depends on the rate at which these interaction can be detected by NMR and analyzed.1D NMR methods most often explore interactions between only few nuclei at a time: spin-spin decoupling measurements are used to demonstrate through-bond connectivity; and NOE measurements are used to probe inter-nuclear distances, 2-Dimensional NMR experiments provide much more structural information in a given time period. Correlation spectroscopy was used to elucidate the aromatic proton position in NMR spectra.

Reference this Research Paper (copy & paste below code):

Kartikeya Dwivedi , Nitin Saraswat , Meena Bisht (2018); Protons Confirmation of Glimepiride drug using Correlation Spectroscopy a unique tool of Nuclear Magnetic Resonance spectroscopy; Int J Sci Res Publ 3(2) (ISSN: 2250-3153). http://www.ijsrp.org/research-paper-0213.php?rp=P14816
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