Abstract: Background: Retro patellar pain resulting from physical & biomechanical changes in patellofemoral joint is described as Patellofemoral Pain Syndrome (PFPS). Incidence for PFPS in India was 22/1000 person in 2010. Females were 2.23 times more likely to develop PFPS compared with males. There have been many studies done using foot orthosis in PFPS for various time intervals in the runners. However there is hardly any study using foot orthosis in PFPS that has shown the effectiveness over a period of 6 weeks in the class 4 workers whose maximum work is in prolong sitting, standing, ascending & descending stairs, bending, walking on a flat surface. Hence, there is a need to study the effectiveness of semi rigid shoe wedge in PFPS in the class 4 workers at Pravara Medical College. Further semirigid shoe wedge can be means of ergonomic aid for treatment of PFPS Objectives: Primary objective of this study is to find out the effectiveness of Semirigid Shoe Wedge in Class IV Workers with Patellofemoral Pain Syndrome. Secondary objective of the study is to compare shoe wedge and Conventional Physiotherapy with Conventional Physiotherapy in reducing pain, Q Angle & improving physical function. Methods: A randomized controlled study was conducted between 2012 and 2013. Ten Class IV Workers with clinical diagnosis of patellofemoral pain syndrome were assigned to two groups where Conventional Physiotherapy was common treatment for each group, while medial full length semirigid shoe wedge was given to experimental group except control one, for the duration of six weeks. Outcome measures used were visual analogue scale (VAS), Q Angle (Q Angle), Western Ontario Mac Master Questionnaire (WOMAC) (Physical Function subscale). Results: The findings of this study showed that all interventions in the form of Semirigid shoe wedge and Conventional Physiotherapy Group (Group A), Conventional Physiotherapy Group (Group B) were effective in reducing pain, Q Angle and improving physical perf