International Journal of Scientific and Research Publications

IJSRP, Volume 9, Issue 1, January 2019 Edition [ISSN 2250-3153]


Molecular and in Silico Studies on DHFR of Uropathogenic Staphylococcus Aureus
      Archana Moon, Pranjali Gajbhiye, Monali Jariya, Deeba Khan, Amit Taksande
Abstract: Urinary tract infections (UTI) are the infection caused by microbes and women are especially prone to it than men due to anatomical reasons. Uropathogenic S.aureus have developed resistant to presently prescribed antibiotics viz., Trimethoprim and cotrimoxazole. S.aureus clinical isolates were utilized in this study.Antibacterial activity for selected phytochemicals was studied.Plasmid DNA isolation and PCR amplification of dfrAgene of DHFR S.aureus was done. In silico studies were performed to analyze the binding efficiencyof various phytochemicals and antibiotics on the DHFR protein of S.aureus.

Reference this Research Paper (copy & paste below code):

Archana Moon, Pranjali Gajbhiye, Monali Jariya, Deeba Khan, Amit Taksande (2019); Molecular and in Silico Studies on DHFR of Uropathogenic Staphylococcus Aureus ; International Journal of Scientific and Research Publications (IJSRP) 9(1) (ISSN: 2250-3153), DOI: http://dx.doi.org/10.29322/IJSRP.9.01.2019.p8575
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