Abstract: The transformative impact of advances in forensic science on the criminal justice system has been profound, significantly influencing the capacity to solve crimes accurately and render just verdicts. This study focuses on the multifaceted aspects of forensic assistance in criminal investigations, with a specific emphasis on its effects and implications in Ghanas Ashanti Region. Through a comprehensive case study, this research aims to provide an in-depth analysis of the challenges, advantages, and policy implications associated with employing sustainable forensic assistance to enhance investigative outcomes. Key stakeholders, including law enforcement officers, forensic specialists, legal practitioners, and government representatives, actively participate in this study, providing valuable insights.